ABSTRACT
COVID-19 is a new disease with high morbidity and mortality in the world and great clinical variability in its behavior. With the aim of characterizing clinical and epidemiological variables in patients positive for COVID-19 in the province of Villa Clara, a descriptive study of positive clinical cases to the real-time Reverse Transcriptase Polymerase Chain Reaction test was carried out. from the province of Villa Clara (317 patients), from March to November 2020. The registry of PCR tests of the Provincial Laboratory of Microbiology was used and the epidemiological surveys were reviewed. Female patients, the age group from 40 to 59 years and residents in the municipality of Santa Clara prevailed. Most of the patients were asymptomatic at diagnosis. The most frequent symptoms were cough and fever. Arterial hypertension and Diabetes Mellitus were the comorbidities that most accompanied the disease.